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I do find it odd that if my wife had arthritis she could probably easily convince a doctor to give her celebrex but for a much more dangerous condition they say no.

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Table 5Complicated and Symptomatic Ulcer Rates in Patients Taking CELEBREX 400 mg Twice DailyKaplan-Meier Rates at 9 monthsBased on Risk Factors.

CardiovascularAggravated hypertensionangina pectoriscoronary artery disordermyocardial infarction.

Known hypersensitivitye.ganaphylactic reactions and serious skin reactionsto celecoxibany components of the drug productsee WARNINGS AND PRECAUTIONSHistory of asthmaurticariaor other allergic-type reactions after taking aspirin or other NSAIDsSeveresometimes fatalanaphylactic reactions to NSAIDshave been reported in such patientssee WARNINGS AND PRECAUTIONSIn the setting of coronary artery bypass graftCABGsurgerysee WARNINGS AND PRECAUTIONSIn patients who have demonstrated allergic-type reactions to sulfonamides.

The incidence of endoscopic ulcers was studied in two 12-weekplacebo-controlled studies in 2157 OA and RA patients in whom baseline endoscopies revealed no ulcersThere was no dose relationship for the incidence of gastroduodenal ulcers and the dose of CELEBREX50 mg to 400 mg twice dailyThe incidence for naproxen 500 mg twice daily was 16.2 and 17.6in the two studiesfor placebo was 2.0 and 2.3and for all doses of CELEBREX the incidence ranged between 2.75.9There have been no largeclinical outcome studies to compare clinically relevant GI outcomes with CELEBREX and naproxen.

Take Celebrex exactly as prescribed by your doctorFollow all directions on your prescription labelDo not take this medicine in larger amounts or for longer than recommendedUse the lowest dose that is effective in treating your condition.

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