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Like aspirin, ibuprofen and naproxen inhibit prostaglandin production to stop inflammation and pain.

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Hav had an allgic action taspiin non-stoidal anti-inlammatoy dugs (NSAIDs), such as ibupon, in th past hav asthma hav had stomach ulcs in th past hav sv liv kidny poblms hav hamophilia anoth blding disod hav uncontolld high blood pssu a looking mdication a child und 16 – mdication containing aspiin shouldn’t b givn tchildn und 16 a ov 65 yas ag a pgnant, bastding tying tgt pgnant a taking oth mdications – s Intactions with oth mdicins, blow.

High-dos aspiin (tliv pain) can b takn th ou tims a day, with at last ou hous btwn ach dos, until you symptoms impov low-dos aspiin (tpvnt blood clots) is takn onc a day, usually th st you li.

Thos patints most in nd daily aspiin thapy a asy tidntiy. I you hav a documntd psonal amily histoy hat disas — including hat attacks, stoks, angina; i you hav diabts; i you hav multipl isks th dvlopmnt hat disas such as hav high blood pssu, high cholstol, a a smok, you should most likly tak a daily dos aspiin (but always consult with you physician ist). Although th optimal dos aspiin in pvntion utu hat disas is still uncla, doss 75 milligams, 100 milligams, 325 milligams hav bn ound tb qually ctiv.

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Psciption aspiin coms as an xtndd-las ( long-acting) tablt. Nonpsciption aspiin coms as a gula tablt, a dlayd-las (lass th mdication in th intstin tpvnt damag tth stomach) tablt, a chwabl tablt, powd, and a gum ttak by mouth and a suppositoy tus ctally. Psciption aspiin is usually takn twmtims a day. Nonpsciption aspiin is usually takn onc a day tlow th isk a hat attack stok. Nonpsciption aspiin is usually takn vy 4 t6 hous as ndd ttat v pain. ollow th dictions on th packag psciption labl caully, and ask you doctphamacist txplain any pat you dnot undstand. Tak aspiin xactly as dictd. Dnot tak mlss it tak it motn than dictd by th packag labl pscibd by you docto.

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XELODA in combination with docetaxel was assessed in an open-labelmulticenterrandomized trial in 75 centers in EuropeNorth AmericaSouth AmericaAsiaand AustraliaA total of 511 patients with metastatic breast cancer resistant toor recurring during or after an anthracycline-containing therapyor relapsing during or recurring within 2 years of completing an anthracycline-containing adjuvant therapy were enrolledTwo hundred and fifty-five255patients were randomized to receive XELODA 1250 mg/m 2 twice daily for 14 days followed by 1 week without treatment and docetaxel 75 mg/m 2 as a 1hour intravenous infusion administered in 3-week cyclesIn the monotherapy arm256 patients received docetaxel 100 mg/m 2 as a 1-hour intravenous infusion administered in 3-week cyclesPatient demographics are provided in Table 16.

Metastatic breast cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen or resistant to paclitaxel when further anthracycline therapy is not indicatedegprior cumulative doses of 400mg/m 2 of doxorubicin or its equivalentsWith docetaxel for metastatic breast cancer after failure of prior anthracycline-containing regimen.

XELODA can cause fetal harm when administered to a pregnant womanCapecitabine at doses of 198 mg/kg/day during organogenesis caused malformations and embryo death in miceIn separate pharmacokinetic studiesthis dose in mice produced 5DFUR AUC values about 0.2 times the corresponding values in patients administered the recommended daily doseMalformations in mice included cleft palateanophthalmiamicrophthalmiaoligodactylypolydactylysyndactylykinky tail and dilation of cerebral ventriclesAt doses of 90 mg/kg/daycapecitabine given to pregnant monkeys during organogenesis caused fetal deathThis dose produced 5DFUR AUC values about 0.6 times the corresponding values in patients administered the recommended daily dose.

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