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Taking metoclopramide may cause you to develop a muscle problem called tardive dyskinesiaIf you develop tardive dyskinesiayou will move your musclesespecially the muscles in your face in unusual waysYou will not be able to control or stop these movementsTardive dyskinesia may not go away even after you stop taking metoclopramideThe longer you take metoclopramidethe greater the risk that you will develop tardive dyskinesiaThereforeyour doctor will probably tell you not to take metoclopramide for longer than 12 weeksThe risk that you will develop tardive dyskinesia is also greater if you are taking medications for mental illnessif you have diabetesor if you are elderlyespecially if you are a womanCall your doctor immediately if you develop any uncontrollable body movementsespecially lip smackingmouth puckeringchewingfrowningscowlingsticking out your tongueblinkingeye movementsor shaking arms or legs.

Risk of developing tardive dyskinesia increases with treatment duration and total cumulative dose.

Metoclopramide IV is approved by the FDA for pediatric use to facilitate small bowel intubation by causing gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.

Metoclopramide injection is used to treat severe diabetic gastroparesisThe injection is also used to prevent nausea and vomiting caused by chemotherapy or surgeryor to aid in certain medical procedures involving the stomach or intestines.

Do not administer for longer than 12 weeksexcept in rare cases where therapeutic benefit is thought to outweigh risk of tardive dyskinesia.

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Methotrexate self-injectable solution may be used as part of a combination therapyThat means you may need to take it with other drugs.

Unfortunatelydepleting the body of folate can affect healthy cellstooespecially those in the gastrointestinalGItractmouthhair follicles and liversays Prabha RanganathanMDan associate professor of medicine in the division of rheumatology at Washington University School of Medicine.

Maintenanceduring remission15 mg/m2 IM or orally twice a weekAlternate remission dosing2.5 mg/kg IV every 14 days.

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