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when deciding upon celebrex as a treatment option, health care providers are urged to carefully consider the risk versus benefit of treatment with celebrex and use the lowest effective dose for the shortest duration of treatment possible to achieve positive therapeutic outcomes.
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in the ongoing battle between celebrx and vioxx, a study presented at the american college of cardiology s meeting in orlando, showed that elderly hypertensive osteoarthritis patient s taking merck s vioxx had an increase in mean systolic blood pressure compared with those taking pharmacia s celebrex, who showed no increase in mean systolic blood pressure.
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in three 12-week studies of pain accompanying oa flare, celebrex doses of 100 mg twice daily and 200 mg twice daily provided significant reduction of pain within 24-48 hours of initiation of dosing.
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