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The following serious adverse reactions are discussed in greater detail in other sections of the label:
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leafletDo not use CRESTOR for a condition for which it was not prescribedDo not give CRESTOR to other peopleeven if they have the same medical condition you haveIt may harm them.
The following adverse reactions have been identified during postapproval use of CRESTORarthralgiafatal and non-fatal hepatic failurehepatitisjaundicethrombocytopeniadepressionsleep disordersincluding insomnia and nightmaresperipheral neuropathy and gynecomastiaBecause these reactions are reported voluntarily from a population of uncertain sizeit is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Rosuvastatin was not mutagenic or clastogenic with or without metabolic activation in the Ames test with Salmonella typhimurium and Escherichia colithe mouse lymphoma assayand the chromosomal aberration assay in Chinese hamster lung cellsRosuvastatin was negative in the in vivo mouse micronucleus test.
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apart from dyslipidemia, crestor has been approved in the u.