Observe patients treated with toprol-xl plus a catecholamine depletor for evidence of hypotension or marked bradycardia, which may produce vertigo, syncope, or postural hypotension.
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based on studies evaluating possible interactions of pantoprazole with other drugs, no dosage adjustment is needed with concomitant use of the following theophylline, cisapride, antipyrine, caffeine, carbamazepine, diazepam and its active metabolite, desmethyldiazepam , diclofenac, naproxen, piroxicam, digoxin, ethanol, glyburide, an oral contraceptive levonorgestrel ethinyl estradiol , metoprolol, nifedipine, phenytoin, warfarin, midazolam, clarithromycin, metronidazole, or amoxicillin.
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if a person is going to undergo surgery, then a high-dose course of toprol xl must not be commenced.
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