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UseAs an adjunct to diet and exerciseto improve glycemic control in adult patients with type 2 diabetes mellitus who are already treated with a thiazolidinedione and sulfonylurea or who have inadequate glycemic control in a thiazolidinedione alone or a sulfonylurea alone.

If you have abdominal or stomach paindark urinea loss of appetitenausea or vomitingunusual tiredness or weaknessor yellow eyes or skincheck with your doctor right awayThese may be symptoms of a serious liver problem.

This medicine may make your skin more sensitive to sunlightUse a sunscreen when you are outdoorsAvoid sunlamps and tanning beds.

Tell your doctor right away if you have any serious side effectsincludingnew/worsening vision problemse.gcolor or night vision problemsbone fracturereddish-colored urineurgent need to urinatepain while urinatingloss of appetiteyellowing eyes/skindark urinemental/mood changese.ghallucinationsconfusionseizureseasy bruising/bleedingsigns of infectione.gfeverpersistent sore throat

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these patients should be started at 1 mg of glimepiride prior to prescribing duetact.

When these medications are withdrawn from a patient receiving duetact, monitor the patient closely for hypoglycemia.

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pioglitazone and glimepiride combination in the elderlyHoweverelderly patients are more likely to have hypoglycemia and age-related kidney problemswhich may require caution and an adjustment in the dose for patients receiving pioglitazone and glimepiride combination.

Use this medication regularly in order to get the most benefit from itRemember to take it at the same time each dayMonitor your blood sugar on a regular basisand share the results with your doctor.

A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

Initial dosepioglitazone 30 mg-glimepiride 2 mg or pioglitazone 30 mg-glimepiride 4 mg orally once a day.

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duetact glimepiride pioglitazone is prescribed by doctors to help their patients get better glycemic control and live better lives.

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Because duetact contains glimepiride, which belongs to the class of sulfonylurea agents, use caution in patients with g6pd deficiency and consider the use of a nonsulfonylurea alternative.

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