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There are no clinical studies establishing the benefit of the combined use of ECT and fluoxetineThere have been rare reports of prolonged seizures in patients on fluoxetine receiving ECT treatment.
Rarelymales may have a painful or prolonged erection lasting 4 or more hoursIf this occursstop using this drug and get medical help right awayor permanent problems could occur.
It should be noted that the diagnosis of PMDD does exist during pregnancyFluoxetine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetusAll pregnancies have a background risk of birth defectslossor other adverse outcome regardless of drug exposure.
Because fluoxetine is tightly bound to plasma proteinsthe administration of fluoxetine to a patient taking another drug that is tightly bound to proteinfor examplewarfarindigitoxinmay cause a shift in plasma concentrations potentially resulting in an adverse effectsee CLINICAL PHARMACOLOGY
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