Baseline characteristics of patients assigned to receive olanzapine or haloperidol .
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there are at least two reported cases of olanzapine-induced pancreatitis doucette et al 2000 ; waage et al 2004 .
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2 of olanzapine-treated patients gained at least 7 of their baseline weight, compared to 3 of placebo-treated patients, with a median exposure to event of 8 weeks; 4.
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89,90 boxed warnings exist for increased risk of death in older patients receiving olanzapine for dementia-related psychosis, and for excessive sedation and delirium following intramuscular injection.
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ethotoin major olanzapine is metabolized by the cyp1a2 hepatic microsomal isoenzyme, and inducers of this enzyme, such as hydantoins, may increase olanzapine clearance.
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summary, this study did not demonstrate significant changes in insulin sensitivity in healthy subjects after 3 wk of treatment with olanzapine or risperidone.
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