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Aspirin or similar medicinesPhenytoinEphedrinea nasal decongestantBarbituratesAntibiotics called rifampicin and rifabutinused to treat tuberculosisAnticoagulant medicines which thin the bloodMedicines for diabetesCertain diureticswater tabletsA medicine called carbamazepineused to treat epilepsypain and manic depressionAn anticancer medicine called aminoglutethimide.

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To learn more about this studyyou or your doctor may contact the study research staff using the contact information provided by the sponsor.

Past studies have revealed high discontinuation rates among men taking dapoxetine for PEeven though trials have shown effectivenessThe current study reported on discontinuation rates and reasons during a 2-year period.

This communication will focus on the prevalenceetiologypathophysiologyand the current treatment options for PEMore specificallya novel selective serotonin reuptake inhibitorSSRIdapoxetinewill be evaluated for its pharmacokineticsefficacyand safety record in light of available preclinical and clinical data.

Expulsion refers to the forcible antegrade propulsion of semen through the urethral meatuswhich is caused by contractions of the periurethral and pelvic floor muscles and concurrent relaxation of the external urethral sphincter and urogenital diaphragmThe sympathetic nervous system controls both emission and bladder neck closureand acts through alpha adrenergic receptorsThe neural signals that lead to ejaculation originate from afferent-sensory stimuli in the glans penis and genitaliaThese stimuli are transmitted by means of the pudendal nerve to higher centers in the brainWitt and Grantmyre 1993

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