When using fluoxetine tablets usp and olanzapine in combination, also refer to the use in specific populations section of the package insert for symbyax.
Information about Olanzapine.
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A lower starting dose5 mgshould be considered for such patientsIn cases of moderate hepatic insufficiencycirrhosisChild-Pugh Class A or Bthe starting dose should be 5 mg and only increased with caution.
The usual oral dose of olanzapine for treating schizophrenia is 10-20 mg once dailyTherapy is initiated with 5-10 mg/dayand the dose may be increased by 5 mg a day at weekly intervalsThe maximum dose is 20 mg dailyThe recommended dose of extended release injection is 150-405 mg every 2 or 4 weeks.
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in clinical trials in elderly patients with dementia, olanzapine treatment was associated with a higher incidence of death and cerebrovascular adverse reactions compared to placebo see section 4.