Global demand is overwhelming fuel supply for reactors after 2017, potentially driving up costs for exelon corp.
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Caregivers should be advised of the high incidence of nausea and vomiting associated with the use of the drug along with the possibility of anorexia and weight lossCaregivers should be encouraged to monitor for these adverse events and inform the physician if they occurIt is critical to inform caregivers that if therapy has been interrupted for more than several daysthe next dose should not be administered until they have discussed this with the physiciansee WARNINGS AND PRECAUTIONS
Overdosage with cholinesterase inhibitors can result in cholinergic crisis characterized by severe nauseavomitingsalivationsweatingbradycardiahypotensionrespiratory depressioncollapse and convulsionsIncreasing muscle weakness is a possibility and may result in death if respiratory muscles are involvedAtypical responses in blood pressure and heart rate have been reported with other drugs that increase cholinergic activity when coadministered with quaternary anticholinergics such as glycopyrrolateAdditional symptoms associated with rivastigmine overdose are diarrheaabdominal paindizzinesstremorheadachesomnolenceconfusional statehyperhidrosishypertensionhallucinations and malaiseDue to the short half-life of rivastigminedialysishemodialysisperitoneal dialysisor hemofiltrationwould not be clinically indicated in the event of an overdose.
Because strategies for the management of overdose are continually evolvingit is advisable to contact a Poison Control Center to determine the latest recommendations for the management of an overdose of any drug.
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exelon expects the permanent financing plan to include a combination of exelon equity issuance, long-term debt and corporate cash.