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In addition to its blood glucose lowering actionsglyburide produces a mild diuresis by enhancement of renal free water clearanceDisulfiram-like reactions have very rarely been reported in patients treated with MICRONASE Tablets.
Often the problem is with specific dosage forms rather than with the active ingredients.
Micronase is a sulfonylurea antidiabetic medicineIt works by causing the pancreas to release insulinwhich helps to lower blood sugar.
Transfer of patients from other oral antidiabetic regimens to MICRONASE should be done conservatively and the initial daily dose should be 2.5 to 5 mgWhen transferring patients from oral hypoglycemic agents other than chlorpropamide to MICRONASEno transition period and no initial or priming dose are necessaryWhen transferring patients from chlorpropamideparticular care should be exercised during the first two weeks because the prolonged retention of chlorpropamide in the body and subsequent overlapping drug effects may provoke hypoglycemia.
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