Do not use this medication if you have severe asthma, emphysema, or other breathing problem, or if you are allergic to promethazine or other phenothiazines such as chlorpromazine thorazine , fluphenazine permitil , perphenazine trilafon , prochlorperazine compazine, compro , thioridazine mellaril , or trifluoperazine stelazine .
Information about Promethazine.
Administration of promethazine HClpromethazine hydrochloridehas been associated with reported cholestatic jaundice.
Get emergency medical help if you have any signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.
CardiovascularIncreased or decreased blood pressuretachycardiabradycardiafaintness.
The black box warning now clearly reads that promethazine hydrochloride injections should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depressionIt also advises caution should be exercised when administering the drug in the form of an injection to patients 2 and older.
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promethazine hydrochloride oral solution should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression.