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Deep vein thrombosis has also been observed in association with clozaril therapy.

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If you miss your doses for longer than a day or twoconsult your doctor for a new schedule to get back to the dose you were onsee Missed Dose sectionUse this medication regularly in order to get the most benefit from itTo help you rememberuse it at the same time(seach day.

Liquid products or dissolving tablets may contain sugar and/or aspartameLiquid products may also contain alcoholCaution is advised if you have diabetesliver diseasephenylketonuriaPKUor any other condition that requires you to limit/avoid these substances in your dietAsk your doctor or pharmacist about using this product safely.

While clozapine can provide great benefitsit can rarely cause seriouspossibly fatal side effectsFor this reasonclozapine is used when other treatments have not worked or you cannot take them.

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You can take clozaril with food or without food, but you just need to be careful what types of foods you take it with.

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Liquid products or dissolving tablets may contain sugar and/or aspartameLiquid products may also contain alcoholCaution is advised if you have diabetesliver diseasephenylketonuriaPKUor any other condition that requires you to limit/avoid these substances in your dietAsk your doctor or pharmacist about using this product safely.

This drug may also cause significant weight gain and a rise in your cholesterolor triglyceridelevelsThese effectsalong with diabetesmay increase your risk for developing heart diseaseDiscuss the risks and benefits of treatment with your doctor.

This medication is used to treat certain mental/mood disordersschizophreniaschizoaffective disordersClozapine is a psychiatric medicationanti-psychotic typethat works by helping to restore the balance of certain natural substancesneurotransmittersin the brain.

Since Clozaril may be associated with thromboembolismimmobilisation of patients should be avoided.

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Mao inhibitors within 14 days – serious, even fatal interactions can occur when taken with tegretol alcohol – when taken with tegretol can dangerously lower blood pressure seldane terfenadine , prozac fluoxetine , luvox fluvoxamine , and rifampin – can lead to drug toxicity tranquilizers, hypnotics, and narcotics – tegretol can increase the effects of these drugs adrenocortical steroids, antidepressants, birth control pills, sandimmune cyclosporine , doxy-ii and vibramycin doxycycline , plendil felodipine , haldol haloperidol , dynacirc isradipine , sporanox itraconazole , tetracyclines, depakene valproic acid , and coumadin warfarin – tegretol can decrease the effects of these drugs clozaril clozapine – can cause serious bone marrow suppression when taken with tegretol felbatol felbamate – can reduce the body s levels of tegretol lithium – taken with tegretol can cause neurological problems such as confusion, tremors, and weakness dilanin phenytoin – can impair seizure control due to fluctuation of blood levels theo-dur theophylline – when taken with tegretol, the effects of both of these drugs can decrease tagamet cimetidine , danocrine danazol , cardizem diltiazem , flu shots, inh isoniazid , erythromycin and other macrolide antibiotics, nicotinamide, darvon propoxyphene , norvir ritonavir , and calan isoptin verapamil – these drugs may increase the effects of tegretol phenobarbital and biaxin clarithromycin – can increase the toxicity of tegretol.

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Clozaril is almost completely metabolized prior to excretion, and only trace amounts of unchanged drug are detected in the urine and feces.

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if clozapine-related systemic disease is suspected, discontinue clozaril immediately.

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