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Before using this medicationtell your doctor or pharmacist your medical historyespecially ofa certain kind of adrenal gland tumorpheochromocytomacerebrovascular diseasee.gstrokeheart problemse.gcongestive heart failureheart attackbleeding problemshistory of severe/frequent headachespeptic ulcerdiabetespersonal/family history of mental/mood disorderse.gschizophreniabipolar disorderpersonal/family history of high blood pressureliver diseaseoveractive thyroidhyperthyroidism

To minimize dizziness and the risk of faintingget up slowly when rising from a sitting or lying position.

Because of the risk of hypertensionco-administration of selegiline and sympathomimetics is contraindicated.

Many drugs can interact with selegilineand some drugs should not be used togetherThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed in this medication guideTell your doctor about all medicines you useand those you start or stop using during your treatment with EldeprylGive a list of all your medicines to any healthcare provider who treats you.

No pharmacokinetic information is available on selegiline or its metabolites in renally impaired subjects.

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Do not use sarafem fluoxetine with eldepryl or emsam selegiline , mellaril thioridazine , or a monoamine oxidase inhibitor maoi including nardil phenelzine , marplan isocarboxazid , azilect rasagiline , parnate tranycypromine , or orap pimozide .

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Because of the risk of confusionhypomaniahallucination and manic episodesagitationmyoclonushyperreflexiaincoordinationshiveringtremorconvulsionataxiadiaphoresisdiarrheafeverhypertensionwhich can be part of the serotonine syndromeconcomitant administration of selegiline and SSRIs or SNRIs is contraindicated.

While you are using Eldepryl and for 14 days after you stopyou must not eat foods listed in theWhat should I avoidsection of this leafletEating these foods while you are using selegiline can raise your blood pressure to dangerous levels.

Before taking selegilinetell your doctor or pharmacist if you are allergic to itor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.

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Do not take this medicine with any of the following medications -duloxetine -levomilnacipran -linezolid -maois like carbex, eldepryl, marplan, nardil, and parnate -methylene blue injected into a vein -milnacipran -venlafaxine this medicine may also interact with the following medications -alcohol -amphetamines -aspirin and aspirin-like medicines -certain migraine headache medicines almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan -dexfenfluramine or fenfluramine -furazolidone -isoniazid -lithium -medicines for heart rhythm or blood pressure -medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin -methylphenidate -metoclopramide -nsaids, medicines for pain and inflammation, like ibuprofen or naproxen -pentazocine -phentermine -procarbazine -protriptyline -rasagiline -sibutramine -st.

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After you stop taking Eldeprylyou must wait at least 14 days before taking any of the medications listed above.

It is not known whether selegiline hydrochloride is excreted in human milkBecause many drugs are excreted in human milkconsideration should be given to discontinuing the use of all but absolutely essential drug treatments in nursing women.

In view of the high degree of binding to plasma proteins by selegiline particular attention must be given to patients who are being treated with medicines with a narrow therapeutic marginindexsuch as digitalis and/or anticoagulants.

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