Nelfinavir , boceprevir, telaprevir nefazodone , as well as gemfibrozil, ciclosporin and danazol.
Information about Danazol.
Since hepatic dysfunction manifested by modest increases in serum transaminase levels has been reported in patients treated with Danazolperiodic liver function tests should be performedsee WARNINGS and ADVERSE REACTIONS
Hepatocellular injuryhepatic failurejaundice hepatocellularhepatocellular focal nodular hyperplasia.
An overdose of danazol is not expected to produce life threatening symptomsHoweverlong term use of high doses can lead to symptoms such as weight gainincreased acne or facial hairmenstrual problemsor breast changes.
Until more is knowncaution is advised in the use of danazol in the presence of known or suspected malignant diseasesee also contraindicationsBefore treatment initiationthe presence of hormone-dependent carcinoma should be excluded at least by careful clinical examinationas well as if breast nodules persist or enlarge during danazol treatmentIn the event of virilisationDanazol should be withdrawnWhilst androgenic reactions will generally prove reversiblecontinued use of danazol in the face of evident virilisation is likely to cause irreversible androgenic effects.
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danazol is present in the form of capsule dosage form.
