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There is a risk of myelosuppressionMonitoring blood counts weekly throughout the duration of therapy should be emphasized to patients taking HYDREAsee WARNINGS AND PRECAUTIONSAdvise patients to report signs and symptoms of infection or bleeding immediatelyAdvise patients that there is a risk of cutaneous vasculitic toxicities and secondary malignancies including leukemia and skin cancerssee WARNINGS AND PRECAUTIONSAdvise females of reproductive potential of the potential risk to a fetus and to inform their healthcare provider of a known or suspected pregnancyAdvise females and males of reproductive potential to use contraception during and after treatment with HYDREAsee WARNINGS AND PRECAUTIONS and Use in Specific PopulationsAdvise patients to inform their healthcare provider if they have received or are planning to receive vaccinations while taking HYDREA as this may result in a severe infectionsee WARNINGS AND PRECAUTIONSAdvise females to discontinue breastfeeding during treatment with HYDREAsee Use in Specific PopulationsPatients with HIV infection should contact their physician for signs and symptoms of pancreatitishepatic eventsand peripheral neuropathysee WARNINGS AND PRECAUTIONSPostirradiation erythema can occur in patients who have received previous irradiation therapysee WARNINGS AND PRECAUTIONS
HYDREA can cause fetal harm when administered to a pregnant womansee Use in Specific PopulationsAdvise females of reproductive potential to use effective contraception during and after treatment with HYDREA for at least 6 months after therapyAdvise females to immediately report pregnancy.
Hydroxyurea is a prescription drugIt comes in two formsa capsule and a tabletYou take both forms by mouth.
Hydroxyurea may cause a drop in platelet countsan important type of blood cells required for forming blood clotsUse of hydroxyurea with anticoagulantsnonsteroidal anti-inflammatory drugsNSAIDsantiplateletsand thrombolytic agents increases the risk of bleeding.
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