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Findings in clinical trialshoweverare not known to reliably predict the abuse potential of drugsNonethelessevidence from single-dose studies does suggest that the recommended daily dosage of bupropion when administered in divided doses is not likely to be especially reinforcing to amphetamine or stimulant abusersHoweverhigher doses that could not be tested because of the risk of seizure might be modestly attractive to those who abuse stimulant drugs.

OBJECTIVEOn the basis of the clinical observations that bupropion facilitated weight losswe investigated the efficacy and tolerability of this drug in overweight and obese adult women.

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John PCunhaDOis a U.Sboard-certified Emergency Medicine PhysicianDrCunha’s educational background includes a BS in Biology from Rutgersthe State University of New Jerseyand a DO from the Kansas City University of Medicine and Biosciences in Kansas CityMOHe completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in NewarkNew Jersey.

Clomidclomipheneis an oral medication used for stimulating ovulationClomid is prescribed to stimulate ovulation in women with ovulatory dysfunction who are not pregnantdo not have abnormal bleeding or ovarian cystsand have normal liver functionIt binds to estrogen receptors in the hypothalamuspituitary glandovaryendometriumvaginaand cervixIt causes production of hormonesgonadotropinsby the pituitarywhich stimulates ovulation.

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