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Though there are not many contraindications to the administering of this drug, patients with hypotension, allergic reactions to the drug components and other intolerances, should not take zyloprim.

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Zyloprim reduces serum and urinary uric acid concentrationsIts use should be individualized for each patient and requires an understanding of its mode of action and pharmacokineticssee CLINICAL PHARMACOLOGYCONTRAINDICATIONSWARNINGSand PRECAUTIONS

Every effort has been made to ensure that the information provided by on this page is accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveThe information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseNeither Everyday Health nor its licensors endorse drugsdiagnose patients or recommend therapyThe drug information above is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safeeffective or appropriate for any given patientNeither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information providedThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have any questions about the drugs you are takingcheck with your doctornurse or pharmacist.

It has been reported that Zyloprim prolongs the half-life of the anticoagulantdicumarolThe clinical basis of this drug interaction has not been established but should be noted when Zyloprim is given to patients already on dicumarol therapy.

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As with bupropionvarenicline is not defined in medical terms as a nicotine replacement therapyHoweverit does function in a similar way.

Due to pharmacokinetic interactions plasma levels of bupropion or its metabolites may be alteredwhich may increase the potential for undesirable effectse.gdry mouthinsomniaseizuresTherefore care should be taken when bupropion is given concomitantly with medicinal products which can induce or inhibit the metabolism of bupropion.

If you have suddenly stopped using alcoholseizure medicationor a sedative such as XanaxValiumFiorinalKlonopinand others

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