Though there are not many contraindications to the administering of this drug, patients with hypotension, allergic reactions to the drug components and other intolerances, should not take zyloprim.

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Zyloprim reduces serum and urinary uric acid concentrationsIts use should be individualized for each patient and requires an understanding of its mode of action and pharmacokineticssee CLINICAL PHARMACOLOGYCONTRAINDICATIONSWARNINGSand PRECAUTIONS

Every effort has been made to ensure that the information provided by on this page is accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveThe information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseNeither Everyday Health nor its licensors endorse drugsdiagnose patients or recommend therapyThe drug information above is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safeeffective or appropriate for any given patientNeither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information providedThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have any questions about the drugs you are takingcheck with your doctornurse or pharmacist.

It has been reported that Zyloprim prolongs the half-life of the anticoagulantdicumarolThe clinical basis of this drug interaction has not been established but should be noted when Zyloprim is given to patients already on dicumarol therapy.

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You may experience acute attacks of gout more often in the early stages of generic zyloprim therapy , even when normal uric acid levels have been attained.

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Pediatric UseZyloprim is rarely indicated for use in children with the exception of those with hyperuricemia secondary to malignancy or to certain rare inborn errors of purine metabolismsee INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION

Kidney functionKidney disease or reduced kidney function may cause this medication to build up in the bodycausing side effectsIf you have reduced kidney function or kidney diseasediscuss with your doctor how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.

In transferring a patient from a uricosuric agent to Zyloprimthe dose of the uricosuric agent should be gradually reduced over a period of several weeks and the dose of Zyloprim gradually increased to the required dose needed to maintain a normal serum uric acid level.

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You should take each dose of allopurinol with a full glass of waterTo reduce the risk of kidney stones formingyou should drink eight to 10 full glasses of fluid every day.

Zyloprim can lower blood cells that help your body fight infectionsThis can make it easier for you to bleed from an injury or get sick from being around others who are illYour blood may need to be tested oftenVisit your doctor regularly.

If you are taking any of these medicationsspeak with your doctor or pharmacistDepending on your specific circumstancesyour doctor may want you to:

Reasonable care has been taken to provide accurate information at the time of creationThis information is not intended to substitute medical advicediagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical conditionPlease refer to our terms and conditions.

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