The co-administration of medications known as proton pump inhibitors such as omeprazole prilosec , lansoprazole prevacid , esomeprazole nexium , pantoprazole protonix , and rabeprazole aciphex , and a medication that provides back protective prostaglandins called misoprostol cytotec can also decrease gastrointestinal bleeding associated with these medications.

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Pantoprazole is used to treat certain stomach and esophagus problemssuch as acid refluxIt works by decreasing the amount of acid your stomach makesThis medication relieves symptoms such as heartburndifficulty swallowingand persistent coughIt helps heal acid damage to the stomach and esophagushelps prevent ulcersand may help prevent cancer of the esophagusPantoprazole belongs to a class of drugs known as proton pump inhibitorsPPIs

Check with your doctor immediately if any of the following side effects occur while taking pantoprazole:

Skin and Subcutaneous Tissue Disorderssevere dermatologic reactionssome fatalincluding erythema multiformeStevens-Johnson syndrometoxic epidermal necrolysisTENangioedemaQuincke’s edemaand cutaneous lupus erythematosus.

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protonix pantoprazole is a member of the proton pump inhibitors drug class and is commonly used for barrett s esophagus, duodenal ulcer, erosive esophagitis, and others.

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In neonatal/juvenile animalsrats and dogstoxicities were similar to those observed in adult animalsincluding gastric alterationsdecreases in red cell massincreases in lipidsenzyme induction and hepatocellular hypertrophyAn increased incidence of eosinophilic chief cells in adult and neonatal/juvenile ratsand atrophy of chief cells in adult rats and in neonatal/juvenile dogswas observed in the fundic mucosa of stomachs in repeated-dose studiesFull to partial recovery of these effects were noted in animals of both age groups following a recovery period.

Applies to pantoprazoleintravenous powder for injectionoral delayed release tabletoral granule enteric coated.

If you are giving the granules through a tube into the stomachnasogastric or gastric tubeask your health care professional for detailed instructions on how to properly mix and give it.

The following adverse reactions have been identified during postapproval use of Protonix and Protonix I.VBecause these reactions are reported voluntarily from a population of uncertain sizeit is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

After oral administration there was a modest increase in the AUC and C max of pantoprazole in women compared to menHoweverweight-normalized clearance values are similar in women and men.

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2Combine the contents of the two vials and further dilute with 80 mL of 5Dextrose InjectionUSP0.9Sodium Chloride InjectionUSPor Lactated Ringer’s InjectionUSPto a total volume of 100 mL with a final concentration of approximately 0.8 mg/mL.

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Very rareless than 0.01Hepatocellular failurecholestatic hepatitis/hepatitisjaundice.

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in other words, powerful acid-suppressing drugs in the proton pump inhibitor category, such as esomeprazole nexium , lansoprazole prevacid , omeprazole prilosec , pantoprazole protonix and rabeprazole aciphex , were linked to an increased risk of heart attacks.