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Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or RenagelTalk to your doctor if you have had difficulty swallowing or swallowing disordersor if you have had digestive tract surgery or other digestive disordersincluding severe constipationThe most common side effects with sevelamer include vomitingnauseadiarrheaupset stomachabdominal painflatulenceand constipationCases of itchingrashfecal impaction andless commonlyslow bowel activitybowel obstructionand bowel perforation have been reportedUncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reportedTalk to your doctor if you have difficulty swallowing medicines in tablet formRenvela powder for oral suspension may be considered by your doctor if you have a history of difficulty swallowingYour doctor should monitor bicarbonate and chloride blood levelsReduced vitamins DEand Kclotting factorsand folic acid blood levels may be followed by your doctorTalk to your doctor when taking sevelamer with other medicationsPromptly contact your doctor if you experience severe abdominal painnew or worsening constipationor other severe intestinal symptoms while on sevelamerTake sevelamer with meals and adhere to your prescribed diet.

Along with its needed effectssevelamerthe active ingredient contained in Renagelmay cause some unwanted effectsAlthough not all of these side effects may occurif they do occur they may need medical attention.

You mayProceed to the site with the understanding that you may experience display or functionality issuesAccess the site using one of the devices running either OS or browsers in the supported list aboveAccess the site on a desktop device.

Along with its needed effectssevelamerthe active ingredient contained in Renagelmay cause some unwanted effectsAlthough not all of these side effects may occurif they do occur they may need medical attention.

In parallel design studies involving 244 haemodialysis patients with treatment duration of up to 54 weeks and 97 peritoneal dialysis patients with treatment duration of 12 weeks were conducted.

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Patients with renal insufficiency may develop hypocalcaemia or hypercalcaemiaRenagel does not contain calciumSerum calcium levels should be monitored as is done in normal follow-up of a dialysis patientElemental calcium should be given as a supplement in case of hypocalcaemia.

During post-marketing experiencevery rare cases of increased phosphate levels have been reported in patients taking proton pump inhibitors co-administered with sevelamer hydrochloride.

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.

Renagel must not be used in people with hypophosphataemialow blood phosphate levelsor with bowel obstructiona blockage in the gut

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Do not take calcium or other mineral supplements without your doctor’s adviceUse only the specific type of calcium or mineral supplement your doctor recommends.

Renagel alone is not indicated for the control of hyperparathyroidismIn patients with secondary hyperparathyroidism Renagel should be used within the context of a multiple therapeutic approachwhich could include calcium supplements1,25-dihydroxy Vitamin D 3 or one of its analogues to lower the intact parathyroid hormoneiPTHlevels.

You should not take Renagel if you are allergic to sevelameror if you have a bowel obstruction.

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