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The combined use of two or more prostaglandinsor prostaglandin analogs including XALATAN is not recommendedIt has been shown that administration of these prostaglandin drug products more than once daily may decrease the IOP lowering effect or cause paradoxical elevations in IOP.
Results showed that the onset of noticeable increased iris pigmentation occurred within the first year of treatment for the majority of the patients who developed noticeable increased iris pigmentationPatients continued to show signs of increasing iris pigmentation throughout the five years of the studyObservation of increased iris pigmentation did not affect the incidencenatureor severity of adverse eventsother than increased iris pigmentationrecorded in the studyIOP reduction was similar regardless of the development of increased iris pigmentation during the study.
If you are wearing contact lensesremove them before using this medicationWait at least 15 minutes before replacing your contact lenses.
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