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Gently mix the oral suspensionliquidby turning the bottle upside down 3 to 5 timesDo not shakeUse the dosing syringe providedor use a medicine dose-measuring devicenot a kitchen spoon

Every effort has been made to ensure that the information provided by Cerner MultumIncMultumis accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveMultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseMultum’s drug information does not endorse drugsdiagnose patients or recommend therapyMultum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safeeffective or appropriate for any given patientMultum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum providesThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have questions about the drugs you are takingcheck with your doctornurse or pharmacist.

Seek medical attention right away if you have symptoms of serotonin syndromesuch asagitationhallucinationsfeversweatingshiveringfast heart ratemuscle stiffnesstwitchingloss of coordinationnauseavomitingor diarrhea.

See ContraindicationsConcomitant sympathomimeticsegpseudoephedrinevasopressive agentsegepinephrinenorepinephrinedopaminergicsegdopaminedobutaminenot recommendedRisk of serotonin syndrome with concomitant SSRIstrycyclic antidepressantstriptansmeperidinebupropionor buspironeAvoid large amounts of dietary tyraminekeep.

Zyvox is indicated in adults for the treatment of community acquired pneumonia and nosocomial pneumonia when known or suspected to be caused by susceptible Gram positive bacteriaIn determining whether Zyvox is an appropriate treatmentthe results of microbiological tests or information on the prevalence of resistance to antibacterial agents among Gram positive bacteria should be taken into considerationsee section 5.1 for the appropriate organisms

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DUse in LIFE-THREATENING emergencies when no safer drug availablePositive evidence of human fetal risk.

Linezolid’s mechanism of action differs from those of other antibiotic classesIn vitro studies with clinical isolatesincluding methicillin-resistant staphylococcivancomycin-resistant enterococciand penicillinand erythromycin-resistant streptococciindicate that linezolid is usually active against organisms which are resistant to one or more other classes of antimicrobial agents.

Intravenous linezolid is injected into a vein through an IVThis medicine must be given slowlyand the IV infusion can take up to 2 hours to completeYou may be shown how to use an IV at homeDo not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needlesIV tubingand other items used to inject the medicine.

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Zyvox solution for infusionfilm-coated tablets or oral suspension may be used as initial therapyPatients who commence treatment on the parenteral formulation may be switched to either oral presentation when clinically indicatedIn such circumstancesno dose adjustment is required as linezolid has an oral bioavailability of approximately 100

To make sure you can safely use linezolidtell your doctor if you have any of these other conditions:

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effectsMany people using this medication do not have serious side effects.

Linezolid should only be initiated in a hospital environment and after consultation with a relevant specialist such as a microbiologist or infectious diseases specialist.

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zyvox is indicated in the treatment of the following infections caused by susceptible strains of the designated microorganisms .