No data are available on the carcinogenic potential of digoxin.
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the dosing recommendations should be reconsidered if patients are elderly or there are other reasons for the renal clearance of digoxin being reduced.
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patients at highest risk for digoxin toxicity include those with renal insufficiency, heart failure, and dehydration.
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with appropriate care, digoxin can be an efficacious, safe, and cost-effective treatment.
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easy method to remember this is the 5,10,15 rule potassium 5 mmol l, dose 10 mg and digoxin level 15 nmol l.
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