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Continue Clozaril treatmentsample blood twice weekly until counts stabilise or increase.
Clozaril can have long lasting effects on your bodyYou may need frequent medical tests for a short time after you stop using this medicine.
Clozaril may enhance the central effects of CNS depressants such as narcoticsantihistamines and benzodiazepinesParticular caution is advised when Clozaril therapy is initiated in patients who are receiving a benzodiazepine or any other psychotropic agentThese patients may have an increased risk of circulatory collapsewhichon rare occasionscan be profound and may lead to cardiac and/or respiratory arrestIt is not clear whether cardiac or respiratory collapse can be prevented by dose adjustment.
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