Clindamycin was compared with ampicillin-sulbactam in 212 patients undergoing head and neck surgery, with 29 infections identified in those treated with clindamycin, versus 14 infections in those treated with ampicillin-sulbactam.
Ampicillin and sulbactam covers skin flora, enteric flora, and anaerobes, but it is not ideal for nosocomial pathogens.
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Ampicillin may also be used for purposes other than those listed in this medication guide.
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Sulbactam is combined with either ampicillin or cefoperazone and this review briefly outlines the in-vitro and clinical characteristics of these combinations.
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