When used for smoking cessation, bupropion zyban usually is started as 150 mg once daily for three days, and then the dose is increased to 150 mg twice daily for 7 to 12 weeks if the patient tolerates the starting dose.

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prasugrel in healthy subjects, prasugrel increased bupropion cmax and auc values by 14 and 18 , respectively, and decreased cmax and auc values of hydroxybupropion by 32 and 24 , respectively.

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, quinidine, bupropion, fluoxetine, and paroxetine see drug interactions 7.

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citalopram plus bupropion helped 30 percent of patients achieve remission, but it s not clear whether this effect is any greater than a placebo effect.

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the effect of hepatic impairment on the pharmacokinetics of bupropion was characterized in 2 single-dose studies, one in patients with alcoholic liver disease and one in patients with mild to severe cirrhosis.
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Aplenzin bupropion hydrobromide 174 mg po qday initially equivalent to 150 mg bupropion hcl ; after 1 week, may increase to usual target dose of 348 mg day equivalent to 300 mg bupropion hcl .

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