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as many patients on uloric 40 mg and up to twice as many on uloric 80 mg reached a healthy uric acid level as those on allopurinol the safety profile of uloric has been evaluated in more than 4000 patients, in some for more than five years.
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in an accompanying comment, dr henry j dargie, scottish advanced heart failure service, golden jubilee national hospital, clydebank, west dunbartonshire, uk and western infirmary, glasgow, uk and dr renjith antony scottish advanced heart failure service, golden jubilee national hospital, clydebank, west dunbartonshire, say although further work is needed to confirm allopurinol s putative anti-ischaemic effects and to better understand its mechanism of action, allopurinol joins a growing list of compounds that tests the conventional wisdom on what constitutes antianginal therapy.
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our main study objective was to study the change in sua with allopurinol versus febuxostat treatment by assessing the proportion of patients achieving a post-index sua goal of 6.
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allopurinol moderate the occurrence of certain hypersensitivity reactions may be increased in patients with renal impairment who receive allopurinol and thiazide diuretics in combination.
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