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Taking esomeprazole long-term may cause you to develop stomach growths called fundic gland polypsTalk with your doctor about this risk.

Diarrhea may be a sign of a new infectionCall your doctor if you have diarrhea that is watery or has blood in it.

Literature suggests that concomitant use of PPIs with methotrexateprimarily at high dosesee methotrexate prescribing informationmay elevate and prolong serum levels of methotrexate and/or its metabolitepossibly leading to methotrexate toxicitiesIn high-dose methotrexate administration a temporary withdrawal of the PPI may be considered in some patientssee DRUG INTERACTIONS

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call your doctor right away if you have watery stool, stomach pain and fever that does not go away bone fractures if you take multiple daily doses of nexium for a year or longer some people who take ppis, including nexium, develop certain types of lupus or have worsening of the lupus they already have.

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Studies designed to investigate the mechanism of gabapentin-induced pancreatic carcinogenesis in rats indicate that gabapentin stimulates DNA synthesis in rat pancreatic acinar cells in vitro andthusmay be acting as a tumor promoter by enhancing mitogenic activityIt is not known whether gabapentin has the ability to increase cell proliferation in other cell types or in other speciesincluding humans.

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