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The management of NMS should include1intensive symptomatic treatment and medical monitoring and 2treatment of any concomitant serious medical problems for which specific treatments are availableDopamine agonistssuch as bromocriptineand muscle relaxantssuch as dantroleneare often used in the treatment of NMShowevertheir effectiveness has not been demonstrated in controlled studies.
If you have not told your doctor about any of the abovetell them before you take any SINEMET.
Do not stop taking SINEMETor lower the dosagewithout checking with your doctor.
If you have trouble remembering to take your tabletsask your pharmacist for some hints.
Patients taking SINEMET alone or with other dopaminergic drugs have reported suddenly falling asleep without prior warning of sleepiness while engaged in activities of daily livingincludes operation of motor vehiclesRoad traffic accidents attributed to sudden sleep onset have been reportedAlthough many patients reported somnolence while on dopaminergic medicationsthere have been reports of road traffic accidents attributed to sudden onset of sleep in which the patient did not perceive any warning signssuch as excessive drowsinessand believed that they were alert immediately prior to the eventSudden onset of sleep has been reported to occur as long as one year after the initiation of treatment.
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try to take sinemet around the same time each day.
